Microcrystalline cellulose is obtained by partial depolymerization and purification under the action of inorganic acid, and its properties are white or off-white powder or granular powder. Almost insoluble in water, ethanol, ether, dilute sulfuric acid or 5% sodium hydroxide solution.
Microcrystalline Cellulose (MCC101) is a high-purity microcrystalline cellulose obtained from high-quality wood pulp or cotton fibers through hydrolysis and purification. Its CAS number is 9004-34-6, and its chemical formula is (C₁₂H₂₀O₁₀)ₙ. It is a white, odorless, and tasteless powder, and is a globally recognized multi-functional industrial excipient. Its unique crystalline structure provides excellent compressibility, flowability, and chemical inertness, playing a core role in solid dosage forms, food processing, and cosmetic formulations. It complies with USP, EP, BP, and Chinese Pharmacopoeia standards, and its safety and compatibility are widely recognized.
Key Features
Multi-functional adaptability: It combines the functions of a filler, binder, disintegrant, and diluent, simplifying formulation systems and improving product uniformity and stability. In direct compression processes, only a small amount of pressure is required to form tablets with excellent strength, while also accelerating drug dissolution and improving bioavailability.
Strict quality standards: Cellulose content 97.0%-102.0%, pH 5.0-7.5, loss on drying ≤5.0%, residue on ignition ≤0.2%; heavy metal content ≤10ppm, strict microbial limits (total bacterial count ≤100cfu/g, mold and yeast ≤20cfu/g), no pathogenic bacteria detected, ensuring application safety.
Excellent physical properties: Bulk density 0.32-0.42g/ml, particle size 80%-100% passing through a 200-mesh sieve, good flowability, easily dispersed evenly, insoluble in water, ethanol, and other common solvents, chemically stable, and does not react with active ingredients.
Products Applications
Pharmaceutical industry: As a core excipient for tablets and capsules, it is suitable for solid dosage forms such as antibiotics, vitamins, and health supplements, with a dosage of 5%-60%, ensuring the integrity and storage stability of the preparations;
Food industry: Used as an anti-caking agent and thickener, improving the texture and taste of baked goods, dairy products, and condiments, and extending shelf life;
Cosmetics industry: As a stabilizer and texture modifier, added to creams, powders, and other products to improve spreadability and formula stability.
Packaging Specifications
Standard packaging is 25kg/sealed bag (with moisture-proof liner), stored in a dry and ventilated environment, with a shelf life of up to 2 years, ensuring stable product performance throughout.
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